Treatment · Zürich Enge
Radiesse®
Radiesse® consists of fine calcium hydroxylapatite microspheres in a soft gel. The gel gives the tissue immediate support; the microspheres then stimulate the body's own collagen formation over months. The firming thus increasingly rests on your own tissue.
At a glance
- From
- CHF 550 · 1.5 ml
- Treatment duration
- 45 minutes
- Downtime
- None, mild swelling possible
- Results visible
- Immediate, final result after about 3 months
- Result lasts
- About 12–18 months

Your treatment will be carried out by Barbara Matziris.
Medical Director · Specialist Physician · Aesthetic Medicine

Indications
What this treatment is suited for
- Declining contour of the cheeks, chin and jawline
- Deeper folds such as nasolabial and marionette lines
- Thin skin on the backs of the hands with visible tendons and veins
- Crêpey, slack skin on the décolleté
Mechanism
How the treatment works
Calcium hydroxylapatite is a mineral that also occurs naturally in bone and teeth. The carrier gel provides immediate volume and is broken down over the following months. The microspheres remain in the tissue for longer and stimulate fibroblasts to form new collagen. Undiluted, Radiesse® supports contours; diluted, it improves skin firmness across larger areas such as the backs of the hands and the décolleté.
Procedure
The treatment procedure
After assessment of contour and skin quality and local anaesthesia, the product is placed with a fine needle or blunt cannula: deep, close to the bone, for contours; diluted and spread beneath the skin for the backs of the hands and the décolleté. The procedure takes approximately 45 minutes. Blood-thinning medication increases the risk of bruising. Whether you can pause it beforehand is something we discuss with you; please never stop it on your own.
Aftercare
After the treatment
Cooling as needed. The area is massaged once immediately after the treatment. No sports or tanning for 48 hours, and no sauna for one week. After treatment of the backs of the hands, rest the hands on the first day.
Risks and side effects
Swelling, redness, tenderness, and bruising are possible in the first few days. Rarely, palpable nodules occur. If nodules persist, become painful, or grow after a treatment, please contact us so the cause can be clarified.
Contraindications
Not suitable during pregnancy and breastfeeding, in the presence of infection or inflammatory skin conditions in the treatment area, with known hypersensitivity to components of the product, with a tendency to keloid formation, or with certain autoimmune conditions. We do not use Radiesse® in the lips or around the eyes.
Questions about the treatment
Frequently asked questions
How does it differ from a hyaluronic acid filler?
Hyaluronic acid fills immediately, can be dissolved if needed, and also suits fine lines and the lips. Radiesse® is firmer, mainly supports contours, and additionally stimulates new collagen over months. The result usually lasts longer but cannot be dissolved. Which product suits you depends on the findings.
How does it differ from HArmonyCa®?
Both contain calcium hydroxylapatite, which stimulates collagen formation. HArmonyCa® combines it with hyaluronic acid and is used mainly across larger areas to firm the face. Radiesse® contains no hyaluronic acid, is somewhat firmer, and is particularly suited to supporting contours such as the cheeks, chin and jawline. Diluted, it can also be used on the backs of the hands and the décolleté. Which product suits you is something we discuss in the consultation.
Can Radiesse® be dissolved?
No. Unlike hyaluronic acid, calcium hydroxylapatite cannot be dissolved with an enzyme; the body breaks it down over time on its own. For this reason dosing is deliberately restrained and the indication carefully reviewed beforehand.
Is the treatment painful?
Most people find it very tolerable. The product contains a local anaesthetic, and on request we also apply a numbing cream beforehand.
How many syringes will I need?
One syringe contains 1.5 ml. The cheeks usually need one to two syringes, the jawline two to three, the backs of the hands or the décolleté one to two. For pronounced lines or marked volume loss, two sessions a few weeks apart are advisable. The price applies per syringe. How much you need is something we decide together in the consultation.
How long does the result last?
About 12 to 18 months, depending on the area and your metabolism. Part of it is visible immediately; the final result shows after around three months, once new collagen has formed.
This information serves general education and does not replace a personal consultation. Whether a treatment is suitable for you is determined solely in the course of an individual medical consultation. Content medically reviewed by Barbara Matziris.
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Consultation for Radiesse®
Whether and to what extent this treatment is suitable for you is clarified in a free initial consultation in our clinic.